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Notes: Y, found to work: positive and statistically significant impacts on the majority of measures assessed within the outcome. M, mixed findings: varied impacts on the outcome; impact varied based on time, subgroup when full sample analyses unreported , or on different measures. N, not found to work: nonsignificant, marginally significant, or negative impacts on the majority of measures assessed within the outcome. US adolescents have high rates of teen pregnancy, childbearing, and sexually transmitted infections STIs , highlighting the need to identify and implement effective programs that will help improve teen sexual and reproductive health. This review identified random-assignment evaluations of 85 programs that incorporated intent-to-treat analyses and assessed impacts on pregnancy, childbearing, STIs, and their key determinants — sexual activity, number of sexual partners, condom use, and other contraceptive use — among teens. This review describes the evidence base for five broad program approaches, including abstinence education, comprehensive sex education, clinic-based programs, youth development programs, and parent—youth relationship programs.

There is evidence that family and friends influence children's decisions to smoke. To assess the effectiveness of interventions to help families stop children starting smoking. We consulted authors and experts in the field. The most recent search was 3 April

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